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Green Synthesis of Silver Nanoparticles Using the Plant Extract of Acer oblongifolium and Study of Its Antibacterial and Antiproliferative Activity via Mathematical Approaches.
Naveed, Muhammad; Bukhari, Bakhtawar; Aziz, Tariq; Zaib, Sumera; Mansoor, Muhammad Adil; Khan, Ayaz Ali; Shahzad, Muhammad; Dablool, Anas S; Alruways, Mashael W; Almalki, Abdulraheem Ali; Alamri, Abdulhakeem S; Alhomrani, Majid.
Afiliação
  • Naveed M; Department of Biotechnology, Faculty of Life Sciences, University of Central Punjab, Lahore 54590, Pakistan.
  • Bukhari B; Department of Biotechnology, Faculty of Life Sciences, University of Central Punjab, Lahore 54590, Pakistan.
  • Aziz T; Pak-Austria Fachhochschule, Institute of Applied Sciences and Technology, Mang, Haripur 22621, Pakistan.
  • Zaib S; Department of Biochemistry, Faculty of Life Sciences, University of Central Punjab, Lahore 54590, Pakistan.
  • Mansoor MA; Department of Chemistry, School of Natural Sciences (SNS), National University of Sciences and Technology (NUST), H-12, Islamabad 44000, Pakistan.
  • Khan AA; Department of Biotechnology, University of Malakand, Chakdara 18800, Pakistan.
  • Shahzad M; Institute of Basic Medical Sciences, Khyber Medical University, Peshawar 25120, Pakistan.
  • Dablool AS; Department of Public Health, Health Sciences College Al-Leith, Umm Al-Qura University, Makkah al-Mukarramah 24382, Saudi Arabia.
  • Alruways MW; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra 15273, Saudi Arabia.
  • Almalki AA; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
  • Alamri AS; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
  • Alhomrani M; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Molecules ; 27(13)2022 Jun 30.
Article em En | MEDLINE | ID: mdl-35807470
In this study, the antibacterial and antifungal properties of silver nanoparticles synthesized with the aqueous plant extract of Acer oblongifolium leaves were defined using a simplistic, environmentally friendly, reliable, and cost-effective method. The aqueous plant extract of Acer oblongifolium, which served as a capping and reducing agent, was used to biosynthesize silver nanoparticles. UV visible spectroscopy, X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and scanning electron microscopy were used to analyze the biosynthesized Acer oblongifolium silver nanoparticles (AgNPs). Gram-positive bacteria (Bacillus paramycoides and Bacillus cereus) and Gram-negative bacteria (E. coli) were used to test the AgNPs' antibacterial activity. The presence of different functional groups was determined by FTIR. The AgNPs were rod-like in shape. The nanoparticles were more toxic against Escherichiacoli than both Bacillus cereus and Bacillus paramycoides. The AgNPs had IC50 values of 6.22 and 9.43 and mg/mL on HeLa and MCF-7, respectively, proving their comparatively strong potency against MCF-7. This confirmed that silver nanoparticles had strong antibacterial activity and antiproliferative ability against MCF-7 and HeLa cell lines. The mathematical modeling revealed that the pure nanoparticle had a high heat-absorbing capacity compared to the mixed nanoparticle. This research demonstrated that the biosynthesized Acer oblongifolium AgNPs could be used as an antioxidant, antibacterial, and anticancer agent in the future.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Bacillus / Acer / Nanopartículas Metálicas Limite: Humans Idioma: En Revista: Molecules Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Bacillus / Acer / Nanopartículas Metálicas Limite: Humans Idioma: En Revista: Molecules Ano de publicação: 2022 Tipo de documento: Article