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No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity.
Barnett, Gillian C; Kerns, Sarah L; Dorling, Leila; Fachal, Laura; Aguado-Barrera, Miguel E; Martínez-Calvo, Laura; Jandu, Harkeran K; Welsh, Ceilidh; Tyrer, Jonathan; Coles, Charlotte E; Haviland, Joanne S; Parker, Christopher; Gómez-Caamaño, Antonio; Calvo-Crespo, Patricia; Sosa-Fajardo, Paloma; Burnet, Neil G; Summersgill, Holly; Webb, Adam; De Ruysscher, Dirk; Seibold, Petra; Chang-Claude, Jenny; Talbot, Christopher J; Rattay, Tim; Parliament, Matthew; De Ruyck, Kim; Rosenstein, Barry S; Pharoah, Paul D P; Dunning, Alison M; Vega, Ana; West, Catharine M L.
Afiliação
  • Barnett GC; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, United Kingdom. Electronic address: gill.barnett@addenbrookes.nhs.uk.
  • Kerns SL; Department of Radiation Oncology, University of Rochester Medical Center, Rochester, New York.
  • Dorling L; Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
  • Fachal L; Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
  • Aguado-Barrera ME; Fundación Pública Galega de Medicina Xenómica (FPGMX)-SERGAS, Santiago de Compostela, A Coruña, Spain; Grupo Genética en Cáncer y Enfermedades Raras, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, A Coruña, Spain.
  • Martínez-Calvo L; Fundación Pública Galega de Medicina Xenómica (FPGMX)-SERGAS, Santiago de Compostela, A Coruña, Spain; Grupo Genética en Cáncer y Enfermedades Raras, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, A Coruña, Spain.
  • Jandu HK; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
  • Welsh C; Department of Oncology, University of Cambridge, Cambridge, United Kingdom.
  • Tyrer J; Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
  • Coles CE; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, United Kingdom.
  • Haviland JS; Clinical Trials and Statistics Unit, Institute of Cancer Research, London, United Kingdom.
  • Parker C; Institute of Cancer Research & Royal Marsden NHS Foundation Trust, London, United Kingdom.
  • Gómez-Caamaño A; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
  • Calvo-Crespo P; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
  • Sosa-Fajardo P; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
  • Burnet NG; Proton Beam Therapy Centre, Christie NHS Foundation Trust, Manchester, United Kingdom.
  • Summersgill H; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust, Manchester, United Kingdom.
  • Webb A; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
  • De Ruysscher D; Department of Radiation Oncology (Maastro Clinic), Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, Maastricht, The Netherlands; Radiation Oncology, Katholieke Universiteit Leuven, Leuven, Belgium.
  • Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany.
  • Talbot CJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
  • Rattay T; Leicester Cancer Research Centre, University of Leicester, Leicester, United Kingdom.
  • Parliament M; Division of Radiation Oncology, Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Canada.
  • De Ruyck K; Departments of Basic Medical Sciences and Radiotherapy, Ghent University Hospital, Ghent, Belgium.
  • Rosenstein BS; Departments of Radiation Oncology and Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
  • Pharoah PDP; Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
  • Dunning AM; Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.
  • Vega A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom; Fundación Pública Galega de Medicina Xenómica (FPGMX)-SERGAS, Santiago de Compostela, A Coruña, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain.
  • West CML; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust, Manchester, United Kingdom.
Int J Radiat Oncol Biol Phys ; 114(3): 494-501, 2022 11 01.
Article em En | MEDLINE | ID: mdl-35840111
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Lesões por Radiação / Produtos Biológicos / Neoplasias da Mama Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Int J Radiat Oncol Biol Phys Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Lesões por Radiação / Produtos Biológicos / Neoplasias da Mama Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Int J Radiat Oncol Biol Phys Ano de publicação: 2022 Tipo de documento: Article