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ZnT8 loss-of-function accelerates functional maturation of hESC-derived ß cells and resists metabolic stress in diabetes.
Ma, Qing; Xiao, Yini; Xu, Wenjun; Wang, Menghan; Li, Sheng; Yang, Zhihao; Xu, Minglu; Zhang, Tengjiao; Zhang, Zhen-Ning; Hu, Rui; Su, Qiang; Yuan, Fei; Xiao, Tinghui; Wang, Xuan; He, Qing; Zhao, Jiaxu; Chen, Zheng-Jun; Sheng, Zhejin; Chai, Mengyao; Wang, Hong; Shi, Weiyang; Deng, Qiaolin; Cheng, Xin; Li, Weida.
Afiliação
  • Ma Q; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Xiao Y; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Xu W; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yueyang Road, 200031, Shanghai, China.
  • Wang M; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Li S; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Yang Z; Department of Physiology and Pharmacology, Karolinska Institute, 17177, Solna, Sweden.
  • Xu M; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Zhang T; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Zhang ZN; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Hu R; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Su Q; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Yuan F; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Xiao T; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Wang X; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • He Q; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Zhao J; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Chen ZJ; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Sheng Z; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Chai M; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Wang H; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Shi W; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Deng Q; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
  • Cheng X; Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Li W; Tsingtao Advanced Research Institute, Tongji University, Qingdao, 266073, China.
Nat Commun ; 13(1): 4142, 2022 07 16.
Article em En | MEDLINE | ID: mdl-35842441
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte de Cátions / Diabetes Mellitus / Células Secretoras de Insulina / Células-Tronco Embrionárias Humanas Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte de Cátions / Diabetes Mellitus / Células Secretoras de Insulina / Células-Tronco Embrionárias Humanas Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2022 Tipo de documento: Article