Influence of Binary Toxin Gene Detection and Decreased Susceptibility to Antibiotics among Clostridioides difficile Strains on Disease Severity: a Single-Center Study.

Costa, Deiziane V S; Pham, Natalie V S; Hays, Rachel A; Bolick, David T; Goldbeck, Sophia M; Poulter, Melinda D; Hoang, Sook C; Shin, Jae H; Wu, Martin; Warren, Cirle A

Costa, Deiziane V S; Pham, Natalie V S; Hays, Rachel A; Bolick, David T; Goldbeck, Sophia M; Poulter, Melinda D; Hoang, Sook C; Shin, Jae H; Wu, Martin; Warren, Cirle A.

Afiliação

Costa DVS; University of Virginiagrid.27755.32, Division of Infectious Diseases and International Health, Charlottesville, Virginia, USA.
Pham NVS; Federal University of Ceara, Department of Physiology and Pharmacology, Fortaleza, Ceara, Brazil.
Hays RA; University of Virginiagrid.27755.32, School of Medicine, Charlottesville, Virginia, USA.
Bolick DT; University of Virginiagrid.27755.32, Division of Gastroenterology and Hepatology, Charlottesville, Virginia, USA.
Goldbeck SM; University of Virginiagrid.27755.32, Division of Infectious Diseases and International Health, Charlottesville, Virginia, USA.
Poulter MD; University of Virginiagrid.27755.32, School of Medicine, Charlottesville, Virginia, USA.
Hoang SC; University of Virginiagrid.27755.32, Department of Pathology, Charlottesville, Virginia, USA.
Shin JH; University of Virginiagrid.27755.32, Department of Surgery, Charlottesville, Virginia, USA.
Wu M; University of Virginiagrid.27755.32, Division of Infectious Diseases and International Health, Charlottesville, Virginia, USA.
Warren CA; University of Virginiagrid.27755.32, Department of Biology, Charlottesville, Virginia, USA.

Antimicrob Agents Chemother ; 66(8): e0048922, 2022 08 16.

Article em En | MEDLINE | ID: mdl-35861541

Assuntos

Toxinas Bacterianas; Clostridioides difficile; Infecções por Clostridium; Adulto; Antibacterianos/farmacologia; Toxinas Bacterianas/genética; Clostridioides; Clostridioides difficile/genética; Infecções por Clostridium/tratamento farmacológico; Fidaxomicina; Humanos; Metronidazol/farmacologia; Testes de Sensibilidade Microbiana; Moxifloxacina; Índice de Gravidade de Doença; Tigeciclina; Vancomicina/farmacologia

Palavras-chave

Clostridioides difficile; antibiotic resistance; binary toxin; fidaxomicin; metronidazole; tigecycline; vancomycin

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Clostridioides difficile / Infecções por Clostridium Tipo de estudo: Diagnostic_studies Limite: Adult / Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2022 Tipo de documento: Article

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