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Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer.
Li, Jiacheng; Liu, Ting; Song, Yuanli; Wang, Mingyu; Liu, Liping; Zhu, Hongwen; Li, Qi; Lin, Jin; Jiang, Hualiang; Chen, Kaixian; Zhao, Kehao; Wang, Mingliang; Zhou, Hu; Lin, Hua; Luo, Cheng.
Afiliação
  • Li J; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Liu T; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Song Y; School of Pharmacy, Fujian Medical University, Fuzhou 350122, China.
  • Wang M; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Liu L; Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Zhu H; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Li Q; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Lin J; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Jiang H; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Chen K; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Zhao K; Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
  • Wang M; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhou H; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Lin H; School of Pharmacy, Fujian Medical University, Fuzhou 350122, China.
  • Luo C; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
J Med Chem ; 65(16): 11034-11057, 2022 08 25.
Article em En | MEDLINE | ID: mdl-35925880
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Quinase 9 Dependente de Ciclina Limite: Humans / Male Idioma: En Revista: J Med Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Quinase 9 Dependente de Ciclina Limite: Humans / Male Idioma: En Revista: J Med Chem Ano de publicação: 2022 Tipo de documento: Article