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Targeting endoplasmic reticulum stress using natural products in neurological disorders.
Jangra, Ashok; Verma, Mehak; Kumar, Deepak; Rachamalla, Mahesh; Dey, Abhijit; Dua, Kamal; Jha, Saurabh Kumar; Ojha, Shreesh; Alexiou, Athanasios; Kumar, Dinesh; Jha, Niraj Kumar.
Afiliação
  • Jangra A; Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.
  • Verma M; Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.
  • Kumar D; Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.
  • Chandrika; Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India.
  • Rachamalla M; Department of Biology, University of Saskatchewan,112 Science Place, Saskatoon, SK S7N 5E2, Canada.
  • Dey A; Department of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700073, West Bengal, India.
  • Dua K; Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Faculty of Health, Australian Research Centre in Complementary & Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia.
  • Jha SK; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Plot No.32-34 Knowledge Park III, Greater Noida, Uttar Pradesh, 201310, India; Department of Biotechnology Engineering and Food Technology, Chandigarh University, Mohali, 140413, India; Department of Biotec
  • Ojha S; Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, Abu Dhabi, United Arab Emirates.
  • Alexiou A; Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, 2770 NSW, Australia. Electronic address: alextha@yahoo.gr.
  • Kumar D; Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, India. Electronic address: dineshbarbola@cuh.ac.in.
  • Jha NK; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Plot No.32-34 Knowledge Park III, Greater Noida, Uttar Pradesh, 201310, India; Department of Biotechnology Engineering and Food Technology, Chandigarh University, Mohali, 140413, India; Department of Biotec
Neurosci Biobehav Rev ; 141: 104818, 2022 10.
Article em En | MEDLINE | ID: mdl-35940309
ABSTRACT
The primary aim of this review is to summarize the literature on natural products that are effective in the treatment of various neurological disorders by targeting endoplasmic reticulum stress (ERS). Various electronic databases such as SCOPUS, PubMed, Web of Science, and Google Scholar were searched for relevant publications. ERS has been implicated in the pathogenesis of numerous neurological disorders such as cerebral ischemia, Parkinson's disease, and Alzheimer's disease. Several natural products targeting ERS signalling pathways provide therapeutic options for neurological diseases, and in this review, the potential neuroprotective properties of these products are discussed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Produtos Biológicos / Fármacos Neuroprotetores / Doença de Alzheimer / Doenças do Sistema Nervoso Limite: Humans Idioma: En Revista: Neurosci Biobehav Rev Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Produtos Biológicos / Fármacos Neuroprotetores / Doença de Alzheimer / Doenças do Sistema Nervoso Limite: Humans Idioma: En Revista: Neurosci Biobehav Rev Ano de publicação: 2022 Tipo de documento: Article