MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats.

Zhang, Feng; Gou, Zhixian; Zhou, Yue; Huang, Lin; Shao, Chunyan; Wang, Minrong; Wu, Chan; Lu, Liqun

Zhang, Feng; Gou, Zhixian; Zhou, Yue; Huang, Lin; Shao, Chunyan; Wang, Minrong; Wu, Chan; Lu, Liqun.

Afiliação

Zhang F; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province
Gou Z; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China.
Zhou Y; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China.
Huang L; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province
Shao C; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province
Wang M; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province
Wu C; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province
Lu L; Clinic Medical College, Chengdu Medical College, No. 783 Xindu Avenue, Xindu District, Chengdu, Sichuan Province 610500, PR China; Department of Pediatrics, The First Affiliated Hospital of Chengdu Medical College, No. 278, Middle Section of Baoguang Avenue, Xindu District, Chengdu, Sichuan Province

Brain Res Bull ; 189: 139-150, 2022 10 15.

Article em En | MEDLINE | ID: mdl-35985609

Assuntos

MicroRNAs; Células Precursoras de Oligodendrócitos; Substância Branca; 2',3'-Nucleotídeo Cíclico Fosfodiesterases/metabolismo; 2',3'-Nucleotídeo Cíclico Fosfodiesterases/farmacologia; Animais; Animais Recém-Nascidos; Antagomirs/farmacologia; Apoptose; DNA Nucleotidilexotransferase/metabolismo; DNA Nucleotidilexotransferase/farmacologia; Lipopolissacarídeos/farmacologia; MicroRNAs/metabolismo; Proteína Básica da Mielina/metabolismo; Proteína Básica da Mielina/farmacologia; Células Precursoras de Oligodendrócitos/metabolismo; Fosfatidilinositol 3-Quinases/metabolismo; Fosfatidilinositóis/farmacologia; Diester Fosfórico Hidrolases/metabolismo; Diester Fosfórico Hidrolases/farmacologia; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Mensageiro; Ratos; Ratos Sprague-Dawley; Tensinas/metabolismo; Substância Branca/metabolismo

Palavras-chave

Apoptosis; Intrauterine infection; Micro-RNA-21-5p; Oligodendrocyte precursor cell; White matter injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Substância Branca / Células Precursoras de Oligodendrócitos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Brain Res Bull Ano de publicação: 2022 Tipo de documento: Article

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