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Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
Rosenberg, Nofar; Van Haele, Matthias; Lanton, Tali; Brashi, Neta; Bromberg, Zohar; Adler, Hanan; Giladi, Hilla; Peled, Amnon; Goldenberg, Daniel S; Axelrod, Jonathan H; Simerzin, Alina; Chai, Chofit; Paldor, Mor; Markezana, Auerlia; Yaish, Dayana; Shemulian, Zohar; Gross, Dvora; Barnoy, Shanny; Gefen, Maytal; Amran, Osher; Claerhout, Sofie; Fernández-Vaquero, Mirian; García-Beccaria, María; Heide, Danijela; Shoshkes-Carmel, Michal; Schmidt Arras, Dirk; Elgavish, Sharona; Nevo, Yuval; Benyamini, Hadar; Tirnitz-Parker, Janina E E; Sanchez, Aranzazu; Herrera, Blanca; Safadi, Rifaat; Kaestner, Klaus H; Rose-John, Stefan; Roskams, Tania; Heikenwalder, Mathias; Galun, Eithan.
Afiliação
  • Rosenberg N; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Van Haele M; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Lanton T; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Brashi N; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Bromberg Z; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Adler H; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Giladi H; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Peled A; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Goldenberg DS; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Axelrod JH; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Simerzin A; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Chai C; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Paldor M; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Markezana A; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Yaish D; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Shemulian Z; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Gross D; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Barnoy S; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Gefen M; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Amran O; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Claerhout S; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium.
  • Fernández-Vaquero M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • García-Beccaria M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Heide D; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Shoshkes-Carmel M; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Center for Translational Research, Philadelphia, USA.
  • Schmidt Arras D; Institut für Biochemie, Christian-Albrechts-Universität zu Kiel, Kiel, Germany; Department of Biosciences, University of Salzburg, Salzburg, Austria.
  • Elgavish S; Bioinformatics Unit, The Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Nevo Y; Bioinformatics Unit, The Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Benyamini H; Bioinformatics Unit, The Institute for Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Tirnitz-Parker JEE; Centre for Medical Research, University of Western Australia & Harry Perkins Institute of Medical Research, Crawley, Australia.
  • Sanchez A; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Spain.
  • Herrera B; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Spain.
  • Safadi R; The Liver Institute, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Kaestner KH; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Center for Translational Research, Philadelphia, USA.
  • Rose-John S; Institut für Biochemie, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.
  • Roskams T; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven and University Hospitals Leuven, Leuven, Belgium.
  • Heikenwalder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany; The M3 Research Institute, Rosenauer Weg 30, Medical Faculty Tuebingen (MFT), 72076 Tuebingen, Germany. Electronic address: m.heikenwaelder@dkfz-heidelberg.de.
  • Galun E; Goldyne Savad Institute of Gene and Cell Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel. Electronic address: eithang@hadassah.org.il.
J Hepatol ; 77(6): 1631-1641, 2022 12.
Article em En | MEDLINE | ID: mdl-35988690
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Hepatol Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Hepatol Ano de publicação: 2022 Tipo de documento: Article