Bisphenol A exposure causes testicular toxicity by targeting DPY30-mediated post-translational modification of PI3K/AKT signaling in mice.

He, Huanshan; Li, Xiang; Shen, Jianing; Bai, Shuying; Li, Cong; Shi, Huaiping

He, Huanshan; Li, Xiang; Shen, Jianing; Bai, Shuying; Li, Cong; Shi, Huaiping.

Afiliação

He H; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Li X; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shen J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Bai S; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Li C; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Shi H; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: huaipingshi@nwafu.edu.cn.

Ecotoxicol Environ Saf ; 243: 113996, 2022 Sep 15.

Article em En | MEDLINE | ID: mdl-36030680

Assuntos

Compostos Benzidrílicos; Fenóis; Testículo; Animais; Compostos Benzidrílicos/toxicidade; Epigênese Genética; Masculino; Camundongos; Fenóis/toxicidade; Fosfatidilinositol 3-Quinases/metabolismo; Processamento de Proteína Pós-Traducional; Proteínas Proto-Oncogênicas c-akt/metabolismo; Sêmen; Testículo/metabolismo; Testículo/patologia; Fatores de Transcrição/metabolismo

Palavras-chave

BPA; DPY30; H3K4me3; PI3K/AKT; Testicular toxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenóis / Testículo / Compostos Benzidrílicos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2022 Tipo de documento: Article

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