The intrinsic quality of proteoglycans, but not collagen fibres, degrades in osteoarthritic cartilage.

Moo, Eng Kuan; Ebrahimi, Mohammadhossein; Sibole, Scott C; Tanska, Petri; Korhonen, Rami K

Moo, Eng Kuan; Ebrahimi, Mohammadhossein; Sibole, Scott C; Tanska, Petri; Korhonen, Rami K.

Afiliação

Moo EK; Department of Applied Physics, University of Eastern Finland, POB 1627, Kuopio 70211, Finland; Human Performance Laboratory, University of Calgary, 2500, University Drive NW, Calgary, Alberta 2N1N4, Canada. Electronic address: engkuan.moo@uef.fi.
Ebrahimi M; Department of Applied Physics, University of Eastern Finland, POB 1627, Kuopio 70211, Finland.
Sibole SC; Human Performance Laboratory, University of Calgary, 2500, University Drive NW, Calgary, Alberta 2N1N4, Canada.
Tanska P; Department of Applied Physics, University of Eastern Finland, POB 1627, Kuopio 70211, Finland.
Korhonen RK; Department of Applied Physics, University of Eastern Finland, POB 1627, Kuopio 70211, Finland. Electronic address: rami.korhonen@uef.fi.

Acta Biomater ; 153: 178-189, 2022 11.

Article em En | MEDLINE | ID: mdl-36113721

Assuntos

Cartilagem Articular; Osteoartrite; Humanos; Proteoglicanas/metabolismo; Análise de Elementos Finitos; Cartilagem Articular/metabolismo; Osteoartrite/patologia; Colágeno/metabolismo

Palavras-chave

Collagen fibre modulus; Fibre-reinforced; Finite element model; Fixed charge density; Multiphasic mixture material; Osteoarthritis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Cartilagem Articular Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Acta Biomater Ano de publicação: 2022 Tipo de documento: Article

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