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Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine-Thiosemicarbazone Derivatives.
Sousa, Gleyton; de Almeida, Maria C F; Lócio, Lucas L; Dos Santos, Vanda L; Bezerra, Daniel P; Silva, Valdenizia R; de Almeida, Sinara M V; Simon, Alice; Honório, Thiago da S; Cabral, Lucio M; Castro, Rosane N; de Moura, Ricardo O; Kümmerle, Arthur E.
Afiliação
  • Sousa G; Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica 23897-000, Brazil.
  • de Almeida MCF; Department of Chemistry, State University of Paraíba, Campina Grande 58429-500, Brazil.
  • Lócio LL; Department of Biological Sciences, State University of Paraíba, Campina Grande 58429-500, Brazil.
  • Dos Santos VL; Department of Biological Sciences, State University of Paraíba, Campina Grande 58429-500, Brazil.
  • Bezerra DP; Department of Biological Sciences, State University of Paraíba, Campina Grande 58429-500, Brazil.
  • Silva VR; Laboratory of Tissue Engineering and Immunopharmacology (LETI), Institute Gonçalo Moniz (IGM), Foundation Oswaldo Cruz (Fiocruz), Salvador 40296-710, Brazil.
  • de Almeida SMV; Laboratory of Tissue Engineering and Immunopharmacology (LETI), Institute Gonçalo Moniz (IGM), Foundation Oswaldo Cruz (Fiocruz), Salvador 40296-710, Brazil.
  • Simon A; Molecular Biology Laboratory, University of Pernambuco (UPE), Garanhuns 55290-000, Brazil.
  • Honório TDS; Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, CCS, Bss, Rio de Janeiro 21941-902, Brazil.
  • Cabral LM; Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, CCS, Bss, Rio de Janeiro 21941-902, Brazil.
  • Castro RN; Department of Drugs and Pharmaceutics, Faculty of Pharmacy, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, CCS, Bss, Rio de Janeiro 21941-902, Brazil.
  • de Moura RO; Institute of Chemistry, Federal Rural University of Rio de Janeiro, Seropédica 23897-000, Brazil.
  • Kümmerle AE; Department of Biological Sciences, State University of Paraíba, Campina Grande 58429-500, Brazil.
Pharmaceuticals (Basel) ; 15(9)2022 Sep 02.
Article em En | MEDLINE | ID: mdl-36145320
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2022 Tipo de documento: Article