Irreversible Bilateral Cicatricial Keratoconjunctivitis after Dupilumab Therapy.
Case Rep Ophthalmol
; 13(2): 638-642, 2022.
Article
em En
| MEDLINE
| ID: mdl-36160495
ABSTRACT
This report highlights a case of irreversible bilateral cicatricial keratoconjunctivitis related to dupilumab therapy for the treatment of severe atopic dermatitis (AD). After 38 years of AD, the patient began dupilumab therapy and achieved disease control. Two years into treatment, his ophthalmic examination was significant for bilateral cicatricial keratoconjunctivitis with severe foreshortening of the inferior conjunctival fornices, symblepharon, and ankyloblepharon, which persisted even after topical steroid eye drops and discontinuation of dupilumab. Treating dermatologists should be aware of this potential irreversible adverse effect, and we recommend that patients are monitored for ocular complications while on dupilumab therapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Case Rep Ophthalmol
Ano de publicação:
2022
Tipo de documento:
Article