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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
Hashimoto, Masao; Araki, Koichi; Cardenas, Maria A; Li, Peng; Jadhav, Rohit R; Kissick, Haydn T; Hudson, William H; McGuire, Donald J; Obeng, Rebecca C; Wieland, Andreas; Lee, Judong; McManus, Daniel T; Ross, James L; Im, Se Jin; Lee, Junghwa; Lin, Jian-Xin; Hu, Bin; West, Erin E; Scharer, Christopher D; Freeman, Gordon J; Sharpe, Arlene H; Ramalingam, Suresh S; Pellerin, Alex; Teichgräber, Volker; Greenleaf, William J; Klein, Christian; Goronzy, Jorg J; Umaña, Pablo; Leonard, Warren J; Smith, Kendall A; Ahmed, Rafi.
Afiliação
  • Hashimoto M; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Araki K; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Cardenas MA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Li P; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Jadhav RR; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Kissick HT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Hudson WH; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.
  • McGuire DJ; Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
  • Obeng RC; Department of Immunology, Mayo Clinic School of Medicine and Sciences, Rochester, MN, USA.
  • Wieland A; Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA.
  • Lee J; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • McManus DT; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Ross JL; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.
  • Im SJ; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
  • Lee J; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Lin JX; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Hu B; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • West EE; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Scharer CD; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Freeman GJ; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Sharpe AH; Department of Pathology, Emory University School of Medicine, Atlanta, GA, USA.
  • Ramalingam SS; Department of Pathology and Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
  • Pellerin A; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Teichgräber V; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Greenleaf WJ; Department of Otolaryngology, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Klein C; The Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
  • Goronzy JJ; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Umaña P; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Leonard WJ; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Smith KA; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
  • Ahmed R; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
Nature ; 610(7930): 173-181, 2022 10.
Article em En | MEDLINE | ID: mdl-36171288
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-2 / Linfócitos T CD8-Positivos / Receptor de Morte Celular Programada 1 Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-2 / Linfócitos T CD8-Positivos / Receptor de Morte Celular Programada 1 Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article