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Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
Bou Sleiman, Maroun; Roy, Suheeta; Gao, Arwen W; Sadler, Marie C; von Alvensleben, Giacomo V G; Li, Hao; Sen, Saunak; Harrison, David E; Nelson, James F; Strong, Randy; Miller, Richard A; Kutalik, Zoltán; Williams, Robert W; Auwerx, Johan.
Afiliação
  • Bou Sleiman M; Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Roy S; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center (UTHSC), Memphis, TN 38163, USA.
  • Gao AW; Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Sadler MC; Institute of Primary Care and Public Health (Unisante), University of Lausanne, Lausanne 1011, Switzerland.
  • von Alvensleben GVG; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.
  • Li H; Department of Computational Biology, University of Lausanne, Lausanne 1015, Switzerland.
  • Sen S; Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Harrison DE; Laboratory of Integrative Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Nelson JF; Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
  • Strong R; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  • Miller RA; Barshop Center for Longevity Studies at the University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
  • Kutalik Z; Barshop Center for Longevity Studies at the University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
  • Williams RW; South Texas Veterans Healthcare System, San Antonio, TX 78229, USA.
  • Auwerx J; Department of Pathology, University of Michigan Geriatrics Center, Ann Arbor, MI 48109-2200, USA.
Science ; 377(6614): eabo3191, 2022 09 30.
Article em En | MEDLINE | ID: mdl-36173858

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Locos de Características Quantitativas / Longevidade Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Locos de Características Quantitativas / Longevidade Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Science Ano de publicação: 2022 Tipo de documento: Article