Clozapine Reduces Recurrent Suicidal and Self-Injurious Behavior in Treatment-Refractory Incarcerated Individuals.
J Correct Health Care
; 28(5): 329-335, 2022 10.
Article
em En
| MEDLINE
| ID: mdl-36178970
ABSTRACT
This retrospective review examines clozapine's effects on treatment-refractory incarcerated individuals (N = 23) with recurrent thoughts of self-harm and/or self-injurious behavior. Emergent suicide risk assessments and days on suicide watch were assessed for the 3 months pre- and post-clozapine treatment. Total suicide assessments fell from 73 pre- to 14 post-clozapine, with a median of 2 assessments (interquartile range [IQR] 1,5) pre-clozapine compared with 0 (IQR 0,1) post-clozapine (p < 0.0001). Total days on suicide watch decreased from 104 days pre- to 32 post-clozapine, with a median of 3 days (IQR 0,9) pre-clozapine compared with 0 (IQR 0,0) post-clozapine (p = 0.0012). Emergency room visits and medical hospitalizations decreased substantially for all months of treatment. Clozapine treatment was associated with marked reductions in self-injurious thoughts and behaviors in high-risk incarcerated individuals.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prisioneiros
/
Suicídio
/
Comportamento Autodestrutivo
/
Clozapina
Limite:
Humans
Idioma:
En
Revista:
J Correct Health Care
Ano de publicação:
2022
Tipo de documento:
Article