Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.

Su, Jun; Li, Yue; Liu, Qing; Peng, Gang; Qin, Chaoying; Li, Yang

Su, Jun; Li, Yue; Liu, Qing; Peng, Gang; Qin, Chaoying; Li, Yang.

Afiliação

Su J; Department of Neurosurgery, Hunan Children's Hospital, No. 86 Ziyuan Road, Changsha, 410007, Hunan, China.
Li Y; Department of Neurosurgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Liu Q; Department of Neurosurgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Peng G; Department of Neurosurgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Qin C; Department of Neurosurgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Li Y; Department of Neurosurgery, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China. ly658872@csu.edu.cn.

J Transl Med ; 20(1): 440, 2022 09 30.

Article em En | MEDLINE | ID: mdl-36180956

Assuntos

Ferroptose; Glioblastoma; Biomarcadores; Proteínas de Ligação a DNA/metabolismo; Regulação Neoplásica da Expressão Gênica; Glioblastoma/patologia; Humanos; Mitocôndrias/metabolismo; Proteínas Mitocondriais/genética; Espécies Reativas de Oxigênio/metabolismo; Sincalida/genética; Sincalida/metabolismo; Sincalida/uso terapêutico; Temozolomida/farmacologia

Palavras-chave

Ferroptosis; Glioblastoma; Mitochondria; SSBP1; Temozolomide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma / Ferroptose Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article

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