Design, synthesis, and pharmacological evaluation of [1, 3] dioxolo-chromeno[2,3-b]pyridines as anti-seizure agents.

Malathi, Visarapu; Sharon, Nissi; Padmaja, Pannala; Lokwani, Deepak; Khadse, Saurabh; Chaudhari, Prashant; Shirkhedkar, Atul A; Reddy, Pedavenkatagari Narayana; Ugale, Vinod G

Malathi, Visarapu; Sharon, Nissi; Padmaja, Pannala; Lokwani, Deepak; Khadse, Saurabh; Chaudhari, Prashant; Shirkhedkar, Atul A; Reddy, Pedavenkatagari Narayana; Ugale, Vinod G.

Afiliação

Malathi V; Department of Chemistry, School of Science, Gitam Deemed to be University, Hyderabad, TS, India.
Sharon N; Department of Chemistry, School of Science, Gitam Deemed to be University, Hyderabad, TS, India.
Padmaja P; Centre for Semio Chemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad, India.
Lokwani D; Rajarshi Shahu College of Pharmacy, Buldana, Maharashtra, India.
Khadse S; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, 425405, India.
Chaudhari P; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, 425405, India.
Shirkhedkar AA; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, 425405, India.
Reddy PN; Department of Chemistry, School of Science, Gitam Deemed to be University, Hyderabad, TS, India. npedaven@gitam.edu.
Ugale VG; Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, 425405, India. vinod.ugale@rediffmail.com.

Mol Divers ; 27(4): 1809-1827, 2023 Aug.

Article em En | MEDLINE | ID: mdl-36214960

Assuntos

Anticonvulsivantes; Piridinas; Anticonvulsivantes/farmacologia; Anticonvulsivantes/uso terapêutico; Anticonvulsivantes/química; Relação Estrutura-Atividade; Piridinas/farmacologia; Piridinas/uso terapêutico; Receptores de GABA-A; Simulação de Dinâmica Molecular; Desenho de Fármacos; Estrutura Molecular

Palavras-chave

Anticonvulsants; Design; Molecular docking; Synthesis; [1,3]Dioxolochromeno[2,3-b]pyridines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Anticonvulsivantes Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Divers Ano de publicação: 2023 Tipo de documento: Article

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