Prodromal α-Synucleinopathies.
Continuum (Minneap Minn)
; 28(5): 1268-1280, 2022 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-36222764
ABSTRACT
PURPOSE OF REVIEW This article describes prodromal α-synucleinopathies. RECENT FINDINGS:
The pathology underlying α-synucleinopathies, which include Parkinson disease, multiple system atrophy, and dementia with Lewy bodies, begins years before the presence of the full syndrome that is the basis for the clinical diagnosis of each of these disorders. This "prodromal" phase may manifest with various signs or symptoms. In addition to individuals in the prodromal phase, some individuals are asymptomatic but are at risk for α-synucleinopathies owing to genetic predisposition or other risk factors.SUMMARY:
Clinicians are increasingly seeing patients in the clinical setting who are prodromal or at risk for α-synucleinopathies, and this article reviews the approach to these patient populations, which includes identifying clinical features, assessment, and counseling.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Atrofia de Múltiplos Sistemas
/
Doença por Corpos de Lewy
/
Sinucleinopatias
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Continuum (Minneap Minn)
Ano de publicação:
2022
Tipo de documento:
Article