Computational prediction of blend time in a large-scale viral inactivation process for monoclonal antibodies biomanufacturing.

Sirasitthichoke, Chadakarn; Hoang, Duc; Phalak, Poonam; Armenante, Piero M; Barnoon, Barak I; Shandil, Ishaan

Sirasitthichoke, Chadakarn; Hoang, Duc; Phalak, Poonam; Armenante, Piero M; Barnoon, Barak I; Shandil, Ishaan.

Afiliação

Sirasitthichoke C; Department of Manufacturing Science and Technology, Bristol Myers Squibb Company, Devens, Massachusetts, USA.
Hoang D; Otto H. York Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.
Phalak P; Department of Manufacturing Science and Technology, Bristol Myers Squibb Company, Devens, Massachusetts, USA.
Armenante PM; Department of Chemical Engineering, University of Massachusetts Lowell, Lowell, Massachusetts, USA.
Barnoon BI; Department of Manufacturing Science and Technology, Bristol Myers Squibb Company, Devens, Massachusetts, USA.
Shandil I; Otto H. York Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, New Jersey, USA.

Biotechnol Bioeng ; 120(1): 169-183, 2023 01.

Article em En | MEDLINE | ID: mdl-36224707

Assuntos

Inativação de Vírus; Vírus; Octoxinol; Anticorpos Monoclonais; Indústria Farmacêutica/métodos

Palavras-chave

CFD analysis; bioprocess; blend time; large scale manufacturing; viral inactivation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus / Inativação de Vírus Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google