Preservation effect of imeglimin on pancreatic ß-cell mass: Noninvasive evaluation using <sup>111</sup>In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements.

Fauzi, Muhammad; Murakami, Takaaki; Fujimoto, Hiroyuki; Botagarova, Ainur; Sakaki, Kentaro; Kiyobayashi, Sakura; Ogura, Masahito; Inagaki, Nobuya

Preservation effect of imeglimin on pancreatic ß-cell mass: Noninvasive evaluation using ¹¹¹In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements.

Fauzi, Muhammad; Murakami, Takaaki; Fujimoto, Hiroyuki; Botagarova, Ainur; Sakaki, Kentaro; Kiyobayashi, Sakura; Ogura, Masahito; Inagaki, Nobuya.

Afiliação

Fauzi M; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Murakami T; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Fujimoto H; Radioisotope Research Center, Agency of Health, Safety, and Environment, Kyoto University, Kyoto, Japan.
Botagarova A; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Sakaki K; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kiyobayashi S; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ogura M; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Inagaki N; Department of Diabetes, Endocrinology, and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Front Endocrinol (Lausanne) ; 13: 1010825, 2022.

Article em En | MEDLINE | ID: mdl-36246910

Assuntos

Diabetes Mellitus Tipo 2; Estado Pré-Diabético; Animais; Estudos Transversais; Citocromos c; Diabetes Mellitus Tipo 2/tratamento farmacológico; Exenatida/farmacologia; Glucose; Hipoglicemiantes/farmacologia; Índio; Camundongos; Mitocôndrias; Tomografia Computadorizada de Emissão de Fóton Único/métodos; Tomografia Computadorizada por Raios X; Triazinas

Palavras-chave

BCM preservation; SPECT/CT; beta cell mass; imeglimin; mitochondria

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estado Pré-Diabético / Diabetes Mellitus Tipo 2 Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2022 Tipo de documento: Article

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