[Detection of paraprotein in plasma cell tumors].
Ter Arkh
; 94(1): 135-144, 2022 Jan 15.
Article
em Ru
| MEDLINE
| ID: mdl-36286929
ABSTRACT
Paraprotein is a laboratory biomarker of plasma cell tumors and other lymphoproliferative diseases. Its determination is necessary for diagnosing, monitoring and assessment of therapy effectiveness. The lecture presents the main methods of qualitative and quantative analysis of monoclonal proteins gel electrophoresis, capillary electrophoresis, immunofixation and nephelometry features, possibilities and limitations are reviewed. The main sources of errors and artifacts during these studies are considered. Also the difficulties in the diagnosis and interpretation of the results of serum and urine tests are highlighted.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmocitoma
/
Mieloma Múltiplo
Tipo de estudo:
Diagnostic_studies
/
Qualitative_research
Limite:
Humans
Idioma:
Ru
Revista:
Ter Arkh
Ano de publicação:
2022
Tipo de documento:
Article