Charting plant gene functions in the multi-omics and single-cell era.
Trends Plant Sci
; 28(3): 283-296, 2023 03.
Article
em En
| MEDLINE
| ID: mdl-36307271
ABSTRACT
Despite the increased access to high-quality plant genome sequences, the set of genes with a known function remains far from complete. With the advent of novel bulk and single-cell omics profiling methods, we are entering a new era where advanced and highly integrative functional annotation strategies are being developed to elucidate the functions of all plant genes. Here, we review different multi-omics approaches to improve functional and regulatory gene characterization and highlight the power of machine learning and network biology to fully exploit the complementary information embedded in different omics layers. Finally, we discuss the potential of emerging single-cell methods and algorithms to further increase the resolution, allowing generation of functional insights about plant biology.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Genes de Plantas
/
Multiômica
Idioma:
En
Revista:
Trends Plant Sci
Ano de publicação:
2023
Tipo de documento:
Article