Spontaneous Escherichia coli Meningitis and Pyogenic Ventriculitis in an Adult Receiving Anti-Tumour Necrosis Factor Alpha Therapy.
Ir Med J
; 114(2): 277, 2021 Feb 18.
Article
em En
| MEDLINE
| ID: mdl-36331959
ABSTRACT
Presentation A 60-year-old male taking etanercept for ankylosing spondylitis was admitted to hospital with confusion and reduced level of consciousness over the preceding 24 hours. Diagnosis Magnetic Resonance Imaging (MRI) of his brain revealed pyogenic ventriculitis, and Escherichia coli was cultured from CSF. Treatment He required placement of an external ventricular drain and was treated with a prolonged course of intravenous ceftriaxone. Conclusion To our knowledge, this is the first reported case of spontaneous Gram-negative bacillary meningitis in a patient on anti-tumour necrosis factor (TNF)-alpha therapy, highlighting the risk of rare but serious infections associated with this class of medication.
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01-internacional
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2_ODS3
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4_TD
Base de dados:
MEDLINE
Idioma:
En
Revista:
Ir Med J
Ano de publicação:
2021
Tipo de documento:
Article