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Capecitabine induces hand-foot syndrome through elevated thymidine phosphorylase-mediated locoregional toxicity and GSDME-driven pyroptosis that can be relieved by tipiracil.
Yang, Bingxue; Xie, Xinran; Lv, Dazhao; Hu, Jiajun; Chen, Yuyun; Wu, Zhaoyu; Luo, Shuyue; Zhang, Shiyi.
Afiliação
  • Yang B; School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
  • Xie X; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Lv D; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Hu J; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Chen Y; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Wu Z; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Luo S; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.
  • Zhang S; School of Pharmacy and School of Biomedical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China. zhangshiyi@sjtu.edu.cn.
Br J Cancer ; 128(2): 219-231, 2023 01.
Article em En | MEDLINE | ID: mdl-36347964
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Síndrome Mão-Pé / Fluoruracila Aspecto: Patient_preference Limite: Animals Idioma: En Revista: Br J Cancer Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Síndrome Mão-Pé / Fluoruracila Aspecto: Patient_preference Limite: Animals Idioma: En Revista: Br J Cancer Ano de publicação: 2023 Tipo de documento: Article