ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy <i>via</i> notch-RBP-J&#954;-H3K4Me3-OSBPL5.

Yang, Juan; Peng, Shuping; Zhang, Keqiang

ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5.

Yang, Juan; Peng, Shuping; Zhang, Keqiang.

Afiliação

Yang J; Department of Gynecologic Oncology Ward 5, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, 12570Central South University, Changsha, China.
Peng S; NHC Key Laboratory of Carcinogenesis of Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, 12570Central South University, Changsha, China.
Zhang K; The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, 12570Central South University, Changsha, China.

Hum Exp Toxicol ; 41: 9603271221135064, 2022.

Article em En | MEDLINE | ID: mdl-36366750

Assuntos

Neoplasias Ovarianas; Humanos; Feminino; Carboplatina/farmacologia; Neoplasias Ovarianas/tratamento farmacológico; Apoptose; Linhagem Celular Tumoral; Autofagia; Fatores de Ribosilação do ADP/genética; Fatores de Ribosilação do ADP/metabolismo

Palavras-chave

ARL4C; OSBPL5; autophagy; carboplatin; cholesterol transport; ovarian cancer

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas Limite: Female / Humans Idioma: En Revista: Hum Exp Toxicol Ano de publicação: 2022 Tipo de documento: Article

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