The study of chemical components in Qishiwei Zhenzhu pills and its anti-apoptotic mechanism in cerebral ischemic based on LC-MS and network pharmacology.

Liang, Yan; Xu, Min; Tang, Ce; Fu, Ke; Li, Xiaoli; Song, Yinglian; Zhang, Jingwen; Wang, Zhang

Liang, Yan; Xu, Min; Tang, Ce; Fu, Ke; Li, Xiaoli; Song, Yinglian; Zhang, Jingwen; Wang, Zhang.

Afiliação

Liang Y; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Xu M; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Tang C; College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China; Innovation Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Fu K; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Li X; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Song Y; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Zhang J; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China.
Wang Z; College of Ethnomedicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, China. Electronic address: wangzhangcqcd@cdutcm.edu.cn.

J Ethnopharmacol ; 302(Pt A): 115891, 2023 Feb 10.

Article em En | MEDLINE | ID: mdl-36368566

Assuntos

Isquemia Encefálica; Medicamentos de Ervas Chinesas; AVC Isquêmico; Animais; Ratos; Proteína X Associada a bcl-2/genética; Proteína X Associada a bcl-2/metabolismo; Caspase 3/metabolismo; Cromatografia Líquida; Ratos Sprague-Dawley; Farmacologia em Rede; Espectrometria de Massas em Tandem; Proteínas Proto-Oncogênicas c-bcl-2/genética; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Isquemia Encefálica/tratamento farmacológico; Infarto Cerebral/tratamento farmacológico; Medicamentos de Ervas Chinesas/farmacologia; Medicamentos de Ervas Chinesas/uso terapêutico; Isquemia/tratamento farmacológico; RNA Mensageiro

Palavras-chave

Antiapoptotic mechanism; Cerebral ischemia; Chemical composition; LC-MS; Network pharmacology; Qishiwei zhenzhu pills

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Isquemia Encefálica / AVC Isquêmico Limite: Animals Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2023 Tipo de documento: Article

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