Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-<i>c</i>]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells.

Nam, Seonghyeon; Lee, Yechan; Park, So-Hyeon; Namkung, Wan; Kim, Ikyon

Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells.

Nam, Seonghyeon; Lee, Yechan; Park, So-Hyeon; Namkung, Wan; Kim, Ikyon.

Afiliação

Nam S; College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Lee Y; College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Park SH; College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Namkung W; College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.
Kim I; College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-ro, Yeonsu-gu, Incheon 21983, Korea.

Pharmaceuticals (Basel) ; 15(11)2022 Nov 12.

Article em En | MEDLINE | ID: mdl-36422525

Palavras-chave

anticancer activity; chemical space; diversity-oriented synthesis; domino reaction; indolizine; liver cancer; multi-component reaction; oxidative cyclization; polyheterocycles; pyrrolo[1,2-c]pyrimidine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2022 Tipo de documento: Article

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