Mulberry Leaf (<i>Morus alba</i> L.) Extracts and Its Chlorogenic Acid Isomer Component Improve Glucolipotoxicity-Induced Hepatic Lipid Accumulation via Downregulating miR-34a and Decreased Inflammation.

Yang, Tsung-Yuan; Yu, Meng-Hsun; Wu, Yi-Liang; Hong, Ching-Chun; Chen, Chin-Shuh; Chan, Kuei-Chuan; Wang, Chau-Jong

Mulberry Leaf (Morus alba L.) Extracts and Its Chlorogenic Acid Isomer Component Improve Glucolipotoxicity-Induced Hepatic Lipid Accumulation via Downregulating miR-34a and Decreased Inflammation.

Yang, Tsung-Yuan; Yu, Meng-Hsun; Wu, Yi-Liang; Hong, Ching-Chun; Chen, Chin-Shuh; Chan, Kuei-Chuan; Wang, Chau-Jong.

Afiliação

Yang TY; Department of Internal Medicine, Chung-Shan Medical University Hospital, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Yu MH; School of Medicine, Institute of Medicine, Chung-Shan Medical University, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Wu YL; Department of Health Industry Technology Management, Chung Shan Medical University, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Hong CC; Department of Nutrition, Chung Shan Medical University, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Chen CS; Division of Cardiovascular Surgery, Surgical Department, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Chan KC; Department of Surgery, School of Medicine, Chung-Shan Medical University, No. 110, Section 1, Jianguo N. Road, Taichung 402, Taiwan.
Wang CJ; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.

Nutrients ; 14(22)2022 Nov 14.

Article em En | MEDLINE | ID: mdl-36432495

Assuntos

Fígado Gorduroso; MicroRNAs; Morus; Ácido Clorogênico/farmacologia; Ácido Clorogênico/metabolismo; Proteína de Ligação a Elemento Regulador de Esterol 1/genética; Proteína de Ligação a Elemento Regulador de Esterol 1/metabolismo; Extratos Vegetais/farmacologia; Extratos Vegetais/metabolismo; Folhas de Planta/metabolismo; Inflamação/tratamento farmacológico; Inflamação/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Fígado Gorduroso/metabolismo; Lipídeos

Palavras-chave

hepatic lipid accumulation and inflammation; miR-34a; mulberry leaf extract; neochlorogenic acid; nonalcoholic fatty liver disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Morus / MicroRNAs / Fígado Gorduroso Tipo de estudo: Prognostic_studies Idioma: En Revista: Nutrients Ano de publicação: 2022 Tipo de documento: Article

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