Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model.

Takaya, Kento; Ishii, Tatsuyuki; Asou, Toru; Kishi, Kazuo

Takaya, Kento; Ishii, Tatsuyuki; Asou, Toru; Kishi, Kazuo.

Afiliação

Takaya K; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.
Ishii T; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.
Asou T; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.
Kishi K; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, Japan.

Aging (Albany NY) ; 14(22): 8914-8926, 2022 11 21.

Article em En | MEDLINE | ID: mdl-36435512

Assuntos

Glutaminase; Pele; Animais; Camundongos; Humanos; Idoso; Camundongos Nus; Fibroblastos/fisiologia; Células Cultivadas; Senescência Celular/fisiologia

Palavras-chave

aging; glutaminase inhibitor; human skin; senescent cell; therapeutic agent

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Glutaminase Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Humans Idioma: En Revista: Aging (Albany NY) Ano de publicação: 2022 Tipo de documento: Article

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