Reversion of glucocorticoid-induced senescence and collagen synthesis decrease by LY294002 is mediated through p38 in skin.

Le, Quoc-Vu; Wen, Su-Ying; Chen, Chih-Jung; Huang, Chih-Yang; Kuo, Wei-Wen

Le, Quoc-Vu; Wen, Su-Ying; Chen, Chih-Jung; Huang, Chih-Yang; Kuo, Wei-Wen.

Afiliação

Le QV; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung 406, Taiwan, ROC.
Wen SY; Ph.D. Program for Biotechnology Industry, China Medical University, Taichung 406, Taiwan, ROC.
Chen CJ; Department of Dermatology, Taipei City Hospital, Renai Branch, Taipei, Taiwan, ROC.
Huang CY; Center for General Education, Mackay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan, ROC.
Kuo WW; Division of Breast Surgery, Department of Surgery, China Medical University Hospital, Taichung 40447, Taiwan, ROC.

Int J Biol Sci ; 18(16): 6102-6113, 2022.

Article em En | MEDLINE | ID: mdl-36439879

Assuntos

Glucocorticoides; Fosfatidilinositol 3-Quinases; Camundongos; Humanos; Animais; Camundongos Endogâmicos C57BL; Receptores de Glucocorticoides; Inibidores de Fosfoinositídeo-3 Quinase; Atrofia

Palavras-chave

LY294002; clobetasol propionate; dermal fibroblasts; glucocorticoid; p38 MAPK; skin atrophy

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Glucocorticoides Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Biol Sci Ano de publicação: 2022 Tipo de documento: Article

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