Toxic shock like syndrome caused by Streptococcus agalactiae bacteremia during treatment for multiple myeloma.
J Infect Chemother
; 29(4): 407-409, 2023 Apr.
Article
em En
| MEDLINE
| ID: mdl-36513293
ABSTRACT
Toxic shock-like syndrome (TSLS) is a life-threatening hyperinflammatory complication caused by Streptococcus species infections. We reported the first case of TSLS caused by primary bacteremia of Streptococcus agalactiae during chemotherapy for multiple myeloma. A 74-year-old woman, who received combination chemotherapy of elotuzumab, pomalidomide, and dexamethasone for treatment-refractory multiple myeloma, was transported to our hospital under comatose and septic shock. Her blood culture detected Streptococcus agalactiae, and considering the progressive multiorgan failure, she was diagnosed with TSLS. Empiric antibiotic treatment with meropenem and respiratory and circulatory support were quickly initiated, resulting in an almost complete recovery of organ functions. It should be noted that with the advances of chemotherapy, the risk of infection is becoming more diverse.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Choque Séptico
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Infecções Estreptocócicas
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Bacteriemia
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Mieloma Múltiplo
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
J Infect Chemother
Ano de publicação:
2023
Tipo de documento:
Article