Whole genome bisulfite sequencing of sperm reveals differentially methylated regions in male partners of idiopathic recurrent pregnancy loss cases.

Irani, Delna; Balasinor, Nafisa; Bansal, Vandana; Tandon, Deepti; Patil, Anushree; Singh, Dipty

Irani, Delna; Balasinor, Nafisa; Bansal, Vandana; Tandon, Deepti; Patil, Anushree; Singh, Dipty.

Afiliação

Irani D; Department of Neuroendocrinology, ICMR - National Institute for Research in Reproductive and Child Health, Mumbai, India.
Balasinor N; Department of Neuroendocrinology, ICMR - National Institute for Research in Reproductive and Child Health, Mumbai, India.
Bansal V; Department of Obstetrics and Gynaecology, Nowrosjee Wadia Maternity Hospital, Mumbai, India.
Tandon D; Department of Clinical Research, ICMR - National Institute for Research in Reproductive and Child Health, Mumbai, India.
Patil A; Department of Clinical Research, ICMR - National Institute for Research in Reproductive and Child Health, Mumbai, India.
Singh D; Department of Neuroendocrinology, ICMR - National Institute for Research in Reproductive and Child Health, Mumbai, India. Electronic address: singhd@nirrch.res.in.

Fertil Steril ; 119(3): 420-432, 2023 03.

Article em En | MEDLINE | ID: mdl-36528109

Assuntos

Aborto Habitual; Metilação de DNA; Placenta; Espermatozoides; Feminino; Humanos; Masculino; Gravidez; Estudos de Casos e Controles; Ilhas de CpG/genética; Metilação de DNA/genética; Placenta/metabolismo; Sêmen/metabolismo; Espermatozoides/metabolismo; Sequenciamento Completo do Genoma; Aborto Habitual/genética; Aborto Habitual/metabolismo; Desenvolvimento Embrionário/genética; Desenvolvimento Embrionário/fisiologia

Palavras-chave

Idiopathic recurrent pregnancy loss; embryo development; placenta development; sperm DNA methylation; whole genome bisulfite sequencing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Placenta / Espermatozoides / Aborto Habitual / Metilação de DNA Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Pregnancy Idioma: En Revista: Fertil Steril Ano de publicação: 2023 Tipo de documento: Article

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