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DGG-300273, a novel WNT/ß-catenin inhibitor, induces apoptotic cell death by activating ROS-BIM signaling in a Wnt-dependent manner in colon cancer cells.
Kim, Do Yeon; Ryu, Yea Seong; Lee, Eun-Sil; Koh, Dong-In; Moon, Jai-Hee; Jung, Soo-A; Kim, Mi Jin; Yun, Hyeseon; You, Ji-Eun; Jeong, Hong-Rae; Yoon, Dong-Il; Kim, Chul Hee; Hong, Seung-Woo; Gong, Young-Dae; Jin, Dong-Hoon.
Afiliação
  • Kim DY; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Ryu YS; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Lee ES; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Koh DI; Innovative Drug-Like Library Research Center, Dongguk University, 30, Pildong-ro 1-gil, Jung-gu, Seoul, 04620, Republic of Korea.
  • Moon JH; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Jung SA; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Kim MJ; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Yun H; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • You JE; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Jeong HR; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Yoon DI; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Kim CH; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Hong SW; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Gong YD; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
  • Jin DH; Asan Institute for Life Science, Asan Medical Center, 88 Olympicro-43gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Invest New Drugs ; 41(1): 105-114, 2023 02.
Article em En | MEDLINE | ID: mdl-36538258
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Beta Catenina Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Beta Catenina Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2023 Tipo de documento: Article