Development of receptor binding domain-based double-antigen sandwich lateral flow immunoassay for the detection and evaluation of SARS-CoV-2 neutralizing antibody in clinical sera samples compared with the conventional virus neutralization test.

Zhang, Ying; Chen, Yixiao; He, Yong; Li, Yizhe; Zhang, Xiaoli; Liang, Jiajie; He, Jinyong; Lu, Shaofang; Gao, Zhixing; Xu, Jianhua; Tang, Yong

Zhang, Ying; Chen, Yixiao; He, Yong; Li, Yizhe; Zhang, Xiaoli; Liang, Jiajie; He, Jinyong; Lu, Shaofang; Gao, Zhixing; Xu, Jianhua; Tang, Yong.

Afiliação

Zhang Y; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China.
Chen Y; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China.
He Y; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China.
Li Y; Department of Laboratory Science, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, 528000, PR China.
Zhang X; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China.
Liang J; Department of Oncology, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, 510632, China.
He J; Department of Laboratory Science, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, 528000, PR China.
Lu S; Department of Laboratory Science, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, 528000, PR China.
Gao Z; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China.
Xu J; Department of Laboratory Science, Shunde Hospital of Guangzhou University of Chinese Medicine, Foshan, 528000, PR China. Electronic address: jhxu1976@gzucm.edu.cn.
Tang Y; Department of Bioengineering, Guangdong Province Engineering Research Center of Antibody Drug and Immunoassay, Jinan University, Guangzhou, 510632, PR China. Electronic address: tyjaq7926@163.com.

Talanta ; 255: 124200, 2023 Apr 01.

Article em En | MEDLINE | ID: mdl-36565525

Assuntos

COVID-19; SARS-CoV-2; Humanos; COVID-19/diagnóstico; Testes de Neutralização; Imunoensaio/métodos; Anticorpos Antivirais; Antígenos; Anticorpos Neutralizantes

Palavras-chave

Double antigen sandwich (DAS); Lateral flow immunoassay (LFIA); Neutralizing antibodies (NAbs); Receptor-binding domain (RBD); SARS-CoV-2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Talanta Ano de publicação: 2023 Tipo de documento: Article

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