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Urinary Citrate Is Associated with Kidney Outcomes in Early Polycystic Kidney Disease.
Rocha, Daniel Ribeiro; Xue, Laixi; Gomes Sousa, Hiago Murilo; Carvalho Matos, Ana Christina; Hoorn, Ewout J; Salih, Mahdi; Heilberg, Ita Pfeferman.
Afiliação
  • Rocha DR; Division of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
  • Xue L; Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Gomes Sousa HM; Division of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
  • Carvalho Matos AC; Division of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
  • Hoorn EJ; Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Salih M; Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Heilberg IP; Division of Nephrology, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.
Kidney360 ; 3(12): 2110-2115, 2022 12 29.
Article em En | MEDLINE | ID: mdl-36591350
Low urinary citrate and crystal deposition accelerated cystogenesis in an experimental model of polycystic kidney disease (PKD).Hypocitraturia, frequently observed in patients with autosomal dominant PKD (ADPKD) could contribute to disease progression.Present findings suggest lower urinary citrate in early PKD was associated with faster eGFR decline and worse kidney survival.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calcinose / Rim Policístico Autossômico Dominante Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Kidney360 Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calcinose / Rim Policístico Autossômico Dominante Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Kidney360 Ano de publicação: 2022 Tipo de documento: Article