Tranilast protects pancreatic ß-cells from palmitic acid-induced lipotoxicity via FoxO-1 inhibition.

Choi, Hye-Eun; Kim, Dong Young; Choi, Mi Jin; Kim, Jea Il; Kim, Ok-Hee; Lee, Jinwook; Seo, Eunhui; Cheon, Hyae Gyeong

Choi, Hye-Eun; Kim, Dong Young; Choi, Mi Jin; Kim, Jea Il; Kim, Ok-Hee; Lee, Jinwook; Seo, Eunhui; Cheon, Hyae Gyeong.

Afiliação

Choi HE; Department of Pharmacology, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
Kim DY; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon, 21999, Republic of Korea.
Choi MJ; Department of Pharmacology, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
Kim JI; Department of Pharmacology, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
Kim OH; Department of Pharmacology, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
Lee J; Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon, 21999, Republic of Korea.
Seo E; Department of Pharmacology, College of Medicine, Gachon University, Incheon, 21999, Republic of Korea.
Cheon HG; College of Pharmacy and Gachon Institute of Pharmaceutical Science, Gachon University, Incheon, 21999, Republic of Korea.

Sci Rep ; 13(1): 101, 2023 01 03.

Article em En | MEDLINE | ID: mdl-36596838

Assuntos

Células Secretoras de Insulina; Ácido Palmítico; Camundongos; Animais; Ácido Palmítico/farmacologia; Células Secretoras de Insulina/metabolismo; Insulina/metabolismo; Apoptose; Glucose/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Palmítico / Células Secretoras de Insulina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google