Transition-Metal-Free Intermolecular Hydrocarbonation of Styrenes Mediated by NaH/1,10-Phenanthroline.
Chemistry
; 29(18): e202203143, 2023 Mar 28.
Article
em En
| MEDLINE
| ID: mdl-36599804
ABSTRACT
A transition-metal-free intermolecular coupling reaction of halocompounds with styrenes in the presence of NaH and 1,10-phenanthroline was developed. This reaction afforded hydrocarbonated products with complete anti-Markovnikov selectivity. The method allows the use of a wide range of halocompounds, including aryl and alkyl halides, and good functional group tolerance. Detailed mechanistic studies indicated that an anilide anion generated inâ
situ by the NaH-mediated reduction of 1,10-phenanthroline works as an electron donor and a hydrogen source.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chemistry
Ano de publicação:
2023
Tipo de documento:
Article