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Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model.
Schalk, Gerwin; Worrell, Samuel; Mivalt, Filip; Belsten, Alexander; Kim, Inyong; Morris, Jonathan M; Hermes, Dora; Klassen, Bryan T; Staff, Nathan P; Messina, Steven; Kaufmann, Timothy; Rickert, Jörn; Brunner, Peter; Worrell, Gregory A; Miller, Kai J.
Afiliação
  • Schalk G; Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States.
  • Worrell S; Chen Frontier Lab for Applied Neurotechnology, Tianqiao and Chrissy Chen Institute, Shanghai, China.
  • Mivalt F; Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States.
  • Belsten A; Department of Neurology, Mayo Clinic, Rochester, MN, United States.
  • Kim I; Department of Biomedical Engineering, Brno University of Technology, Brno, Czechia.
  • Morris JM; Department of Neurosurgery, Washington University in St. Louis, St. Louis, MO, United States.
  • Hermes D; National Center for Adaptive Neurotechnologies, Albany, NY, United States.
  • Klassen BT; Department of Neurology, Mayo Clinic, Rochester, MN, United States.
  • Staff NP; Department of Neuroradiology, Mayo Clinic, Rochester, MN, United States.
  • Messina S; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.
  • Kaufmann T; Department of Neurology, Mayo Clinic, Rochester, MN, United States.
  • Rickert J; Department of Neurology, Mayo Clinic, Rochester, MN, United States.
  • Brunner P; Department of Neuroradiology, Mayo Clinic, Rochester, MN, United States.
  • Worrell GA; Department of Neuroradiology, Mayo Clinic, Rochester, MN, United States.
  • Miller KJ; CorTec GmbH, Freiburg, Germany.
Front Neurosci ; 16: 932782, 2022.
Article em En | MEDLINE | ID: mdl-36601593
ABSTRACT
This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Neurosci Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Neurosci Ano de publicação: 2022 Tipo de documento: Article