Syringeable atorvastatin loaded eugenol enriched PEGylated cubosomes in-situ gel for the intra-pocket treatment of periodontitis: statistical optimization and clinical assessment.

Elgendy, Heba Amin; Makky, Amna M A; Elakkad, Yara E; Ismail, Radwa M; Younes, Nihal Farid

Elgendy, Heba Amin; Makky, Amna M A; Elakkad, Yara E; Ismail, Radwa M; Younes, Nihal Farid.

Afiliação

Elgendy HA; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt.
Makky AMA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Elakkad YE; Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt.
Ismail RM; Department of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Misr University for Science and Technology, Giza, Egypt.
Younes NF; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

Drug Deliv ; 30(1): 2162159, 2023 Dec.

Article em En | MEDLINE | ID: mdl-36604813

Assuntos

Eugenol; Periodontite; Humanos; Atorvastatina/uso terapêutico; Eugenol/uso terapêutico; Periodontite/tratamento farmacológico; Inflamação/tratamento farmacológico; Polietilenoglicóis; Tamanho da Partícula

Palavras-chave

Box-Behnken design; Intra-pocket delivery; and clinical assessment; atorvastatin; cubosomes; periodontitis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Periodontite / Eugenol Limite: Humans Idioma: En Revista: Drug Deliv Ano de publicação: 2023 Tipo de documento: Article

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