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The value of anti-rods and rings antibodies in Chinese population of Dalian City: A retrospective study.
Gu, Yanan; Li, Si; Wang, Zhen; Yang, Dong.
Afiliação
  • Gu Y; Department of Clinical Laboratory, First Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Li S; Department of Clinical Laboratory, First Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Wang Z; Department of Clinical Laboratory, First Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Yang D; Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Scand J Immunol ; 97(6): e13254, 2023 Jun.
Article em En | MEDLINE | ID: mdl-36626120
The study aimed to investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear antibodies (ANAs) test samples retrospectively. The laboratory data and clinical details of patients with positive anti-RR antibodies were collected and analysed between December 2017 and May 2022 in the First Affiliated Hospital of Dalian Medical University. A total of 72 665 patients were tested for ANAs. There were 45 632 patients discovered with positive ANAs (62.80%), only 131 patients presented with anti-RR antibodies (0.18%), among which only 68 patients were hospitalized patients with a definitive diagnosis. Among the 68 patients with a definitive diagnosis, 8 of 68 (11.8%) had autoimmune diseases, and 19 of 68 (27.9%) had renal diseases. Other diseases included liver disease, pulmonary disease, cerebral ischemia, cerebral infarction, chronic cardiac failure and venous thromboembolism. The detection rate of high titre(≥1:1000) anti-RR antibodies is significantly higher in autoimmune diseases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / População do Leste Asiático Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Scand J Immunol Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / População do Leste Asiático Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Scand J Immunol Ano de publicação: 2023 Tipo de documento: Article