Colchicine as potential inhibitor targeting MMP-9, NOX2 and TGF-ß1 in myocardial infarction: a combination of docking and molecular dynamic simulation study.

Suryono, Suryono; Rohman, Mohammad Saifur; Widjajanto, Edi; Prayitnaningsih, Seskoati; Wihastuti, Titin Andri

Suryono, Suryono; Rohman, Mohammad Saifur; Widjajanto, Edi; Prayitnaningsih, Seskoati; Wihastuti, Titin Andri.

Afiliação

Suryono S; Doctoral Program of Medical Science, Brawijaya University, Malang, East Java, Indonesia.
Rohman MS; Department of Cardiology and Cardiovascular Medicine, Faculty of Medicine, Jember University, Jember, East Java, Indonesia.
Widjajanto E; Department of Cardiology and Cardiovascular Medicine, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
Prayitnaningsih S; Brawijaya Cardiovascular Research Centre, Brawijaya University, Malang, East Java, Indonesia.
Wihastuti TA; Department of Clinical Pathology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.

J Biomol Struct Dyn ; 41(21): 12214-12224, 2023.

Article em En | MEDLINE | ID: mdl-36636837

Assuntos

Infarto do Miocárdio; Fator de Crescimento Transformador beta1; Humanos; Fator de Crescimento Transformador beta1/metabolismo; Simulação de Dinâmica Molecular; Colchicina/farmacologia; Metaloproteinase 9 da Matriz/metabolismo; Remodelação Ventricular/fisiologia; Simulação de Acoplamento Molecular; Infarto do Miocárdio/tratamento farmacológico; Infarto do Miocárdio/metabolismo

Palavras-chave

Colchicine; MMP-9; NOX2; TGF-ß1; in silico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta1 / Infarto do Miocárdio Limite: Humans Idioma: En Revista: J Biomol Struct Dyn Ano de publicação: 2023 Tipo de documento: Article

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