Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-<i>ß</i>1/Smad pathway in MN mice.

Li, Yongzhang; Chen, Suzhi; Tan, Jinchuan; Zhou, Yan; Ren, Meifang; Zhang, Qian; Zhao, Meijiao; Yuan, Guodong; Zhang, Wenxi; Yang, Fengwen

Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-ß1/Smad pathway in MN mice.

Li, Yongzhang; Chen, Suzhi; Tan, Jinchuan; Zhou, Yan; Ren, Meifang; Zhang, Qian; Zhao, Meijiao; Yuan, Guodong; Zhang, Wenxi; Yang, Fengwen.

Afiliação

Li Y; Department of Urology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Chen S; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Tan J; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Zhou Y; Department of Urology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Ren M; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Zhang Q; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Zhao M; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Yuan G; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Zhang W; Department of Pharmacy, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.
Yang F; Department of Nephrology, Hebei Province of Chinese Medicine, Shijiazhuang City, Hebei Province, China.

Ren Fail ; 45(1): 2120821, 2023 Dec.

Article em En | MEDLINE | ID: mdl-36648018

Assuntos

Glomerulonefrite Membranosa; Nefropatias; Podócitos; Camundongos; Humanos; Animais; Fator de Crescimento Transformador beta1/metabolismo; Podócitos/metabolismo; Nefropatias/metabolismo; Fibrose; Imunoglobulina G/metabolismo; Proteínas Smad

Palavras-chave

Membranous nephropathy; TGF-ß1/Smad; bone marrow mesenchymal stem cells; dihydroartemisinin; podocyte injury; renal fibrosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glomerulonefrite Membranosa / Podócitos / Nefropatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Ren Fail Ano de publicação: 2023 Tipo de documento: Article

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