The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway.

Shao, Yankun; Xu, Yilin; Di, Huang; Shi, Xinxiu; Wang, Yingying; Liu, Hongyu; Song, Lina

Shao, Yankun; Xu, Yilin; Di, Huang; Shi, Xinxiu; Wang, Yingying; Liu, Hongyu; Song, Lina.

Afiliação

Shao Y; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Xu Y; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Di H; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Shi X; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Wang Y; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Liu H; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.
Song L; Department of Neurology, China-Japan Union Hospital of JiLin University, Changchun, China.

IET Nanobiotechnol ; 17(3): 182-196, 2023 May.

Article em En | MEDLINE | ID: mdl-36680386

Assuntos

Doença de Alzheimer; Ferroptose; Doenças Neurodegenerativas; Camundongos; Animais; Doença de Alzheimer/prevenção & controle; Camundongos Endogâmicos C57BL; Modelos Animais de Doenças; RNA Mensageiro; Proteínas de Membrana/genética

Palavras-chave

Alzheimer's disease; ORMDL3; PERK; ferroptosis

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Doença de Alzheimer / Ferroptose Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: IET Nanobiotechnol Ano de publicação: 2023 Tipo de documento: Article

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