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Optimization of BAX trigger site activator BTSA1 with improved antitumor potency and in vitro ADMET properties.
Zhang, Zhenwei; Zhao, Shan; Pei, Jiying; Hou, Linghui; Luan, Shenglin; Deng, Hongguang; Liu, Dan; Huang, Min; Zhao, Linxiang.
Afiliação
  • Zhang Z; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Zhao S; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Pei J; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Hou L; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Luan S; China Resources Sanjiu Medical & Pharmaceutical Co., Ltd., Shenzhen, China.
  • Deng H; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Liu D; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
  • Huang M; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: huangcrazye@sina.com.
  • Zhao L; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: linxiang.zhao@vip.sina.com.
Eur J Med Chem ; 248: 115076, 2023 Feb 15.
Article em En | MEDLINE | ID: mdl-36680883
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Membranas Mitocondriais Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Membranas Mitocondriais Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article