Modified Gegen Qinlian decoction ameliorates DSS-induced chronic colitis in mice by restoring the intestinal mucus barrier and inhibiting the activation of Î³Î´T17 cells.

Ma, Jing; Zhang, Jiaqi; Wang, Yifan; Huang, Jinke; Yang, Xuefei; Ma, Jinxin; Liu, Zhihong; Wang, Fengyun; Tang, Xudong

Ma, Jing; Zhang, Jiaqi; Wang, Yifan; Huang, Jinke; Yang, Xuefei; Ma, Jinxin; Liu, Zhihong; Wang, Fengyun; Tang, Xudong.

Afiliação

Ma J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Zhang J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Wang Y; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Huang J; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Yang X; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Ma J; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Liu Z; Department of Gastroenterology, Peking University Traditional Chinese Medicine Clinical Medical School (Xiyuan), 100091, Beijing, China.
Wang F; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Tang X; Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: txdly@sina.com.

Phytomedicine ; 111: 154660, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36681051

Assuntos

Colite Ulcerativa; Colite; Animais; Camundongos; Colite/induzido quimicamente; Colite/tratamento farmacológico; Colite Ulcerativa/induzido quimicamente; Colite Ulcerativa/tratamento farmacológico; Colite Ulcerativa/metabolismo; Colo/patologia; Sulfato de Dextrana/toxicidade; Modelos Animais de Doenças; Inflamassomos/metabolismo; Camundongos Endogâmicos C57BL; Muco; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo

Palavras-chave

Modified Gegen Qinlian decoction; NLRP3 inflammasome; Ulcerative colitis; Î³Î´T17 cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Colite Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Phytomedicine Ano de publicação: 2023 Tipo de documento: Article

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