Your browser doesn't support javascript.
loading
Advances in MDS/AML and inositide signalling.
De Stefano, Alessia; Marvi, Maria Vittoria; Fazio, Antonietta; McCubrey, James A; Suh, Pann-Ghill; Ratti, Stefano; Ramazzotti, Giulia; Manzoli, Lucia; Cocco, Lucio; Follo, Matilde Y.
Afiliação
  • De Stefano A; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Marvi MV; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Fazio A; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • McCubrey JA; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, USA.
  • Suh PG; Korea Brain Research Institute, Daegu, Republic of Korea; School of Life Sciences, UNIST, Ulsan, Republic of Korea.
  • Ratti S; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Ramazzotti G; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Manzoli L; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Cocco L; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
  • Follo MY; Department of Biomedical Sciences (DIBINEM), University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy. Electronic address: matilde.follo@unibo.it.
Adv Biol Regul ; 87: 100955, 2023 01.
Article em En | MEDLINE | ID: mdl-36706610
ABSTRACT
Aberrant signaling pathways regulating proliferation and differentiation of hematopoietic stem cells (HSCs) can contribute to disease pathogenesis and neoplastic growth. Phosphoinositides (PIs) are inositol phospholipids that are implicated in the regulation of critical signaling pathways aberrant regulation of Phospholipase C (PLC) beta1, PLCgamma1 and the PI3K/Akt/mTOR pathway play essential roles in the pathogenesis of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML).
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda Limite: Humans Idioma: En Revista: Adv Biol Regul Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda Limite: Humans Idioma: En Revista: Adv Biol Regul Ano de publicação: 2023 Tipo de documento: Article