MCB-613 exploits a collateral sensitivity in drug resistant <i>EGFR</i>-mutant non-small cell lung cancer through covalent inhibition of KEAP1.

Bassil, Christopher F; Anderson, Gray R; Mayro, Benjamin; Askin, Kayleigh N; Winter, Peter S; Gruber, Samuel; Hall, Tierney M; Hoj, Jacob P; Cerda-Smith, Christian; Hutchinson, Haley M; Killarney, Shane T; Singleton, Katherine R; Qin, Li; Jubien-Girard, Kévin; Favreau, Cécile; Martin, Anthony R; Robert, Guillaume; Benhida, Rachid; Auberger, Patrick; Pendergast, Ann Marie; Lonard, David M; Puissant, Alexandre; Wood, Kris C

MCB-613 exploits a collateral sensitivity in drug resistant EGFR-mutant non-small cell lung cancer through covalent inhibition of KEAP1.

Bassil, Christopher F; Anderson, Gray R; Mayro, Benjamin; Askin, Kayleigh N; Winter, Peter S; Gruber, Samuel; Hall, Tierney M; Hoj, Jacob P; Cerda-Smith, Christian; Hutchinson, Haley M; Killarney, Shane T; Singleton, Katherine R; Qin, Li; Jubien-Girard, Kévin; Favreau, Cécile; Martin, Anthony R; Robert, Guillaume; Benhida, Rachid; Auberger, Patrick; Pendergast, Ann Marie; Lonard, David M; Puissant, Alexandre; Wood, Kris C.

Afiliação

Bassil CF; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Anderson GR; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Mayro B; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Askin KN; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Winter PS; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Gruber S; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Hall TM; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Hoj JP; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Cerda-Smith C; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Hutchinson HM; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Killarney ST; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Singleton KR; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Qin L; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.
Jubien-Girard K; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR 7272 - 06108 Nice, France.
Favreau C; Université Côte d'Azur, INSERM, C3M, Nice, France.
Martin AR; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR 7272 - 06108 Nice, France.
Robert G; IBMM, Université de Montpellier, ENSCM, CNRS, Montpellier, France.
Benhida R; Université Côte d'Azur, INSERM, C3M, Nice, France.
Auberger P; Université Côte d'Azur, CNRS, Institut de Chimie de Nice UMR 7272 - 06108 Nice, France.
Pendergast AM; Chemical & Biochemical Sciences Green-Process Engineering (CBS) Mohammed VI Polytechnic University, Lot 660, Hay Moulay Rachid, Benguerir, Morocco.
Lonard DM; Université Côte d'Azur, INSERM, C3M, Nice, France.
Puissant A; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
Wood KC; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.

bioRxiv ; 2023 Jan 19.

Article em En | MEDLINE | ID: mdl-36711936

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article

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