Protein dynamics provide mechanistic insights about epistasis among common missense polymorphisms.

Ose, Nicholas J; Campitelli, Paul; Patel, Ravi; Kumar, Sudhir; Ozkan, S Banu

Ose, Nicholas J; Campitelli, Paul; Patel, Ravi; Kumar, Sudhir; Ozkan, S Banu.

Afiliação

Ose NJ; Department of Physics and Center for Biological Physics, Arizona State University, Tempe, Arizona.
Campitelli P; Department of Physics and Center for Biological Physics, Arizona State University, Tempe, Arizona.
Patel R; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania; Department of Biology, Temple University, Philadelphia, Pennsylvania.
Kumar S; Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, Pennsylvania; Department of Biology, Temple University, Philadelphia, Pennsylvania; Center for Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: s.kumar@temple.edu.
Ozkan SB; Department of Physics and Center for Biological Physics, Arizona State University, Tempe, Arizona. Electronic address: banu.ozkan@asu.edu.

Biophys J ; 122(14): 2938-2947, 2023 07 25.

Article em En | MEDLINE | ID: mdl-36726312

Assuntos

Evolução Biológica; Epistasia Genética; Humanos; Mutação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epistasia Genética / Evolução Biológica Limite: Humans Idioma: En Revista: Biophys J Ano de publicação: 2023 Tipo de documento: Article

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