PSC-derived intestinal organoids with apical-out orientation as a tool to study nutrient uptake, drug absorption and metabolism.

Kakni, Panagiota; López-Iglesias, Carmen; Truckenmüller, Roman; Habibovic, Pamela; Giselbrecht, Stefan

Kakni, Panagiota; López-Iglesias, Carmen; Truckenmüller, Roman; Habibovic, Pamela; Giselbrecht, Stefan.

Afiliação

Kakni P; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.
López-Iglesias C; Microscopy CORE lab, Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Maastricht, Netherlands.
Truckenmüller R; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.
Habibovic P; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.
Giselbrecht S; MERLN Institute for Technology-Inspired Regenerative Medicine, Department of Instructive Biomaterials Engineering, Maastricht University, Maastricht, Netherlands.

Front Mol Biosci ; 10: 1102209, 2023.

Article em En | MEDLINE | ID: mdl-36743212

Palavras-chave

barrier integrity; drug discovery; epithelial polarity; gastrointestinal model; intestinal organoids; nutrient uptake

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Idioma: En Revista: Front Mol Biosci Ano de publicação: 2023 Tipo de documento: Article

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