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Overview of the role and action mechanism of microRNA-128 in viral infections.
Alshahrani, Shadia Hamoud; Alameri, Ameer A; Kahar, Fitriani; Alexis Ramírez-Coronel, Andrés; Fadhel Obaid, Rasha; Alsaikhan, Fahad; Zabibah, Rahman S; Qasim, Qutaiba A; Altalbawy, Farag M A; Fakri Mustafa, Yasser; Mirzaei, Rasoul; Karampoor, Sajad.
Afiliação
  • Alshahrani SH; Medical Surgical Nursing Department, King Khalid University, Almahala, Khamis Mushate, Saudi Arabia.
  • Alameri AA; Department of Chemistry, University of Babylon, Babylon, Iraq.
  • Kahar F; Medic Technology Laboratory, Poltekkes Kemenkes Semarang, Indonesia.
  • Alexis Ramírez-Coronel A; National University of Education, Azogues, Ecuador; Catholic University of Cuenca, Azogues Campus, Ecuador; University of Palermo, Buenos Aires, Argentina; CES University, Colombia, Azogues, Ecuador.
  • Fadhel Obaid R; Department of Biomedical Engineering, Al-Mustaqbal University College, Babylon, Iraq.
  • Alsaikhan F; College of Pharmacy, Prince Sattam Bin Abdulaziz University, Alkharj, Kingdom of Saudi Arabia.
  • Zabibah RS; Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq.
  • Qasim QA; College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq.
  • Altalbawy FMA; National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt; Department of Chemistry, University College of Duba, Tabuk University, Duba 71911, Saudi Arabia.
  • Fakri Mustafa Y; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul 41001, Iraq.
  • Mirzaei R; Venom and Biotherapeutics Molecules Lab, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Electronic address: rasul.micro92@gmail.com.
  • Karampoor S; Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran. Electronic address: karampour.s@iums.ac.ir.
Microb Pathog ; 176: 106020, 2023 Mar.
Article em En | MEDLINE | ID: mdl-36746316
Recently in vivo and in vitro studies have provided evidence establishing the significance of microRNAs (miRNAs) in both physiological and pathological conditions. In this regard, the role of miRNA-128 (miR-128) in health and diseases has been found, and its critical regulatory role in the context of some viral diseases has been recently identified. For instance, it has been found that miR-128 can serve as an antiviral mediator and significantly limit the replication and dissemination of human immunodeficiency virus type 1 (HIV-1). Besides, it has been noted that poliovirus receptor-related 4 (PVRL4) is post-transcriptionally regulated by miR-128, representing possible miRNA targets that can modulate measles virus infection. Of note, the downregulation of seminal exosomes eca-miR-128 is associated with the long-term persistence of Equine arteritis virus (EAV) in the reproductive tract, and this particular miRNA is a putative regulator of chemokine ligand 16 (C-X-C motif) as determined by target prediction analysis. In this review, the latest information on the role and action mechanism of miR-128 in viral infections will be summarized and discussed in detail.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viroses / MicroRNAs Limite: Animals / Humans Idioma: En Revista: Microb Pathog Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Viroses / MicroRNAs Limite: Animals / Humans Idioma: En Revista: Microb Pathog Ano de publicação: 2023 Tipo de documento: Article